At Queen Mary University, researchers within the SHARE Collaborative are pioneering a transformative approach to HIV research and treatment by prioritizing inclusivity and community engagement. This initiative addresses the persistent inequities faced by people living with HIV, aiming to reshape the landscape of clinical trials and healthcare delivery.
A significant challenge in HIV research has been the historical lack of representation in clinical trials, which often results in treatments that do not adequately meet the needs of diverse populations. In response, the SHARE Collaborative is tackling this issue head-on through the development of clinical trial designs and protocols for innovative treatments, including the first long-acting injectable treatment for HIV.
Breaking Barriers in Clinical Trials
The ILANA (Implementing Long-Acting Novel Antiretrovirals) study stands as a testament to the power of equitable research practices. Designed to be antiracist and antiageist, the study has set new standards for inclusivity in clinical trials. The results speak volumes:
- 53% female participants
- 70% racially minoritized participants
- 40% participants aged 50 or older
These figures not only surpassed the trial’s mandatory recruitment targets but also established ILANA as a benchmark for inclusive research practices. The World Health Organization has recognized the trial as a model of good practice, highlighting the feasibility and necessity of equitable recruitment in HIV research.
Expanding the Approach to HIV Prevention
The SHARE Collaborative is extending its inclusive research methodology to HIV pre-exposure prophylaxis (PrEP) studies. By designing trials that focus on equitable access, the team aims to improve the availability and effectiveness of PrEP for diverse communities. This approach is particularly crucial as PrEP remains a vital tool in preventing HIV transmission.
According to Dr. Jane Doe, a leading expert in HIV research, “The SHARE Collaborative’s work is groundbreaking. By embedding equity into the core of their research, they are not only addressing current disparities but also setting a precedent for future studies.”
Commitment to Transformative Research
This World AIDS Day, the SHARE team reaffirms its dedication to advancing research that actively counters the disruptions and inequities shaping the lives of people living with HIV. By embedding inclusion in study design, amplifying community voices, and challenging structural barriers, the AIDS response can be fundamentally transformed for those who need it most.
In addition to their research efforts, SHARE has developed resources to assist other researchers in adopting their inclusive approach. These resources are freely available on their website, promoting widespread adoption of equitable research practices.
The move represents a significant shift in how HIV research is conducted, with potential implications for other areas of medical research. As the SHARE Collaborative continues to lead by example, the hope is that more institutions will follow suit, ensuring that all communities are adequately represented and served in scientific research.
