The Early Detection of Liver Disease research project, known as ID LIVER, has reached a significant milestone by enrolling over 2000 patients. This initiative, spearheaded by researchers at Manchester University NHS Foundation Trust (MFT) and The University of Manchester (UoM), aims to transform the diagnosis and management of liver disease, particularly in underserved communities. By leveraging expertise from the Innovate UK-funded project, the study is developing innovative pathways to identify, assess, and manage at-risk patients effectively.
In the past year alone, more than 600 participants have been assessed in community settings across Greater Manchester as part of the Health Innovation Accelerator. This initiative is a component of the Advanced Diagnostics Accelerator (ADA), which seeks to address major diseases affecting the 2.8 million residents of Greater Manchester.
Innovative Approaches to Early Detection
The ID LIVER project is shifting the paradigm of liver disease care towards early detection and intervention. According to Stephanie Landi, Clinical Research Hepatology Fellow at MFT, the project is breaking down barriers to access by bringing liver health assessments directly into communities. This approach is crucial as liver disease often goes undetected until it reaches an advanced stage.
“ID LIVER is shifting the focus of liver disease care towards early detection and intervention. By bringing liver health assessments directly into communities, we are removing barriers to access and reaching people who might otherwise present much later with advanced disease,” said Stephanie Landi.
One of the key aspects of the project is its focus on areas of high socioeconomic deprivation, where liver disease disproportionately impacts residents. By targeting these communities, the project ensures that care reaches those who need it most, empowering individuals to make informed decisions about their liver health before complications arise.
Community Impact and Personal Stories
Health Innovation Manchester recently highlighted the story of Tony, a 68-year-old resident of Greater Manchester, who participated in the ID LIVER health check following a referral from his General Practitioner (GP). Tony’s experience underscores the accessibility and patient-centered nature of the project.
“An appointment was made for me… I turned up and it was all very pleasant, there was no stress, no worry – I just turned up, did the test which was a scan, and that was it. The opportunity is there and there are people out there who want to help you,” Tony shared.
The project utilizes the state-of-the-art Greater Manchester Research Van, operated by MFT, to conduct screenings in easily accessible locations. This mobile unit is unique to the region and aims to increase public participation in research, thereby enhancing the quality and inclusivity of the studies conducted.
Expert Insights and Future Directions
Oliver Street, Programme Manager at The University of Manchester, emphasized the importance of early detection and prevention, noting that symptoms of liver disease often do not appear until the disease is advanced and irreversible damage has occurred. By identifying and assessing at-risk patients early, the project supports timely treatment and improved care pathways.
“Early detection and prevention of liver disease is extremely important because often symptoms do not present until the disease is advanced and damage to the liver is irreversible,” said Oliver Street.
Daniel Zamora, Programme Director at Health Innovation Manchester, praised the project’s targeted approach and its positive impact on disease treatment across Greater Manchester. The Health Innovation Accelerator continues to shape how patients are identified and treated through innovative solutions in various care settings.
“This project is another fantastic example of how a targeted approach for early detection and community screening is having a lasting positive impact on the treatment of disease for people across Greater Manchester,” stated Daniel Zamora.
As the ID LIVER study progresses, it represents a critical step forward in addressing liver disease in Greater Manchester. The project’s success thus far highlights the potential for similar initiatives to improve health outcomes in other regions, ultimately contributing to a broader understanding and management of liver disease on a national scale.
